log IC 50 and log IC 30 for antagonist: Spreadsheet antagonist Spreadsheet for use with kDPRA in TG 442C log PC 10, log PC 50 and RPC max for agonist assay: Spreadsheet agonist This reporting format has been slightly adapted to meet the needs of the Guideline on Defined Approaches on Skin Sensitisation ( Word) Spreadsheets for use with TG 458 QSAR Model Reporting Format to be used with TG 497 (DASS) In: A Dhawan, M Bajpayee (eds), Genotoxicity Assessment: Methods and Protocols, Methods in Molecular Biology, vol 2031, Humana, NY, NY. This document is a pre-print from a book chapter on Erythrocyte-Based Pig-a Gene Mutation Assay ( PDF)īemis JC, NE Hall, SD Dertinger (2019) Erythrocyte-based Pig-a gene mutation assay. For use of the software under Good Laboratory Practice, the validation status should be checked and any additional validation performed as appropriate.Įxample of a protocol for the Mammalian Erythrocyte Pig -a Gene Mutation Assay (TG 470) The maintenance of the software or of the calculation sheets is not guaranteed by the OECD. It is also not a requirement to use this material, and other software for example may be equally useful. Green growth and sustainable developmentĭisclaimer: the software package, spreadsheets or protocols available for some Test Guidelines are provided as a courtesy of the developer of the test method, but have not been necessarily validated, reviewed or approved by the OECD.
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